In RPCS3, click File > Add Games and select the folder containing your Spider-Man: Edge of Time game files.
Playing the game via emulation legally requires owning a physical copy of the game disc and dumping the software to a PC. Common stable emulators capable of running the console versions include: For emulating the PlayStation 3 version. Xenia: For emulating the Xbox 360 version. Dolphin: For emulating the Nintendo Wii version.
An alternative for running the Xbox 360 version of the game. Dolphin (Wii Emulator):
